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A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer

✍ Scribed by Ho-Pun-Cheung, A; Assenat, E; Bascoul-Mollevi, C; Bibeau, F; Boissière-Michot, F; Thezenas, S; Cellier, D; Azria, D; Rouanet, P; Senesse, P; Ychou, M; Lopez-Crapez, E

Book ID
121724060
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
256 KB
Volume
11
Category
Article
ISSN
1470-269X

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## Abstract ## Purpose To identify if thymidine phosphorylase (TP), dihydropyrimidine dehydrogenase (DPD), and ratio TP/DPD levels in tumor tissues are potential predictive factors for response to combined preoperative chemoradiation with capecitabine, in patients with locally advanced rectal canc