## Abstract ## Background Localized gene transfer to salivary glands has great potential for the treatment of salivary gland, systemic, and oral diseases. The minipig parotid gland, given its volume and morphological similarities to the human parotid gland, may be useful as a large animal model fo
✦ LIBER ✦
A large preclinical animal model to assess ex vivo skin gene therapy applications
✍ Scribed by Wolfgang Pfützner; Mohammed R. Joari; Ruth-Ann Foster; Jonathan C. Vogel
- Book ID
- 106078639
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 416 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0340-3696
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## Background: Inefficiency, aspecificity and toxicity of gene transfer vectors hamper gene therapy from showing its full potential. on this basis significant research currently focuses on developing vectors with improved infection and/or expression profiles. screening assays with validity to the c