A Laboratory Study to Assess Separate and In-combination Effects of Zinc, Chromium and Nickel to the FishMystus vittatus
✍ Scribed by Verma, S. R. ;Jain, M. ;Dalela, R. C.
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 389 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0323-4320
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The present investigation is designed to work out the isolated and in‐combination effects of Zn^2+^, Cr^6+^ and Ni^2+^ to a fish Mystus vittatus.
From all the 12 combinations, 6 are antagonistic and 6 are synergistic.
The combination Cr/Ni is highly synergistic while combination (Cr + Ni)/Zn is highly antagonistic in nature.
The possible mechanisms responsible for antagonistic and synergistic combinations have been discussed and indicated as the occupation of critical receptor sites by less toxic metal (antagonism) or intrinsic affinity of the individual metal for the critical site or relative concentration and distribution of the metals within the target organ site (synergism).
The results drawn can be indicated in terms of the effective concentration required to reach a particular level for a particular biological end point and can be expressed as follows.
📜 SIMILAR VOLUMES
## Abstract An escalating‐dose trial of idarubicin, used weekly for 3 doses in combination with vincristine, prednisone, and L‐asparaginase (VPLI), to reinduce remission of childhood ALL at first bone marrow relapse was conducted by the Childrens Cancer Study Group (CCSG). The maximum tolerated dos