## Abstract The K562 cell line, which was established from a patient with chronic myeloid leukemia in blast crisis, was thought to be myeloid, but recent data indicate that it is an undifferentiated erythroid cell line. We have found that the glycosphingolipid content of these cells differs conside
A kinetic and clonal analysis of heterogeneity in K562 cells
β Scribed by Susan Alder; A. Ciampi; E. A. McCulloch
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 683 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The major obstacle preventing effective treatment of melanoma is the biological heterogeneity of tumor cells. This study was performed to determine clonal genetic heterogeneity within primary melanoma and the evolution of these heterogeneous sub-clones during disease progression. DNA samples were ob
## Abstract The cell surface antigen, CD38, is a bifunctional ectoβenzyme, which is predominantly expressed on hematopoietic cells during differentiation. In the present study, it is shown that hemin treatment of K562 cells gives rise to induction of enzymatic activities inherent to CD38. GDPβribos
Natural killer (NK) cells bind to K562 tumor target cells in vitro and kill them. The binding and cytotoxic activities of NK cells are tightly related to each other: degranulation of the cytotoxic effector is the basis for target cell damage and a consequence of effector-target recognition and bindi