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A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation

✍ Scribed by Tadashi Furumoto; Aki Tanaka; Mitsuhiro Ito; Sohail Malik; Yutaka Hirose; Fumio Hanaoka; Yoshiaki Ohkuma

Book ID: 108731907
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 330 KB
Volume: 12
Category: Article
ISSN: 1356-9597
DOI: 10.1111/j.1365-2443.2007.01036.x

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## Abstract This study tested the hypothesis that an osteoclastic protein‐tyrosine phosphatase, PTP‐oc, enhances osteoclast activity through c‐Src activation. The effects of several resorption activators and inhibitors on PTP‐oc expression, resorption activity, and c‐Src activation were determined