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A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth

✍ Scribed by Kim, Seyun; Wong, Pauline; Coulombe, Pierre A.


Book ID
109895758
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
422 KB
Volume
441
Category
Article
ISSN
0028-0836

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## Abstract Cultured human retinal pigment epithelial cells (RPE) secrete insulin‐like growth factor binding proteins (IGFBPs), a family of polypeptides which modulate the actions of the insulin‐like growth factors. RPE cells secrete two IGFBPs with Mr estimates of 34,000 and 46,000, respectively.