A Japanese case with an unusual variant of chromosome 16 with an extra C-negative, G-dark segment in the short arm

Mapping of the breakpoints on the short

Mapping of the breakpoints on the short arm of chromosome 17 in neoplasms with an i(17q)

✍ Wolfram G. Scheurlen; Georg C. Schwabe; Peter Seranski; Stefan Joos; Jochen Harb 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 368 KB 👁 2 views

Isochromosomes are monocentric or dicentric chromosomes with homologous arms that are attached in a reverse configuration as mirror images. With an incidence of 3-4%, the i(17q) represents the most frequent isochromosome in human cancer. It is found in a variety of tumors, particularly in blast cris