✦ LIBER ✦

A hypothesis to explain the enigmatic natural history of neuroblastoma

✍ Scribed by Cassady, J. Robert

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 440 KB
Volume: 12
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950120115

No coin nor oath required. For personal study only.

✦ Synopsis

A hypothesis is developed for neuroblastoma that attempts to explain the enigmatic natural history of this tumor and the variation in success of therapy as a function of the age of the child at diagnosis. It is postulated that neuroblastoma arising in the young patient has a relative paucity of clonogenically viable stem cells, whereas tumors arising in the older children have a substantial number of such clonogenic cells, as in most human tumors.

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