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A Hyperthermophilic Protein Acquires Function at the Cost of Stability†

✍ Scribed by Mukaiyama, Atsushi; Haruki, Mitsuru; Ota, Motonori; Koga, Yuichi; Takano, Kazufumi; Kanaya, Shigenori

Book ID
115530954
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
118 KB
Volume
45
Category
Article
ISSN
0006-2960

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## Abstract __Pyrococcus furiosus__, a hyperthermophilic archaeon growing optimally at 100°C, encodes three protein chaperones, a small heat shock protein (sHsp), a prefoldin (Pfd), and a chaperonin (Cpn). In this study, we report that the passive chaperones sHsp and Pfd from __P. furiosus__ can bo