A hydroxyapatite coating covalently linked onto a silicone implant material

✍ Scribed by Furuzono, Tsutomu ;Sonoda, Kensaku ;Tanaka, Junzo

• Book ID: 101340557
• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 404 KB
• Volume: 56
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/1097-4636(200107)56:1<9::aid-jbm1073>3.0.co;2-2

✦ Synopsis

A novel composite consisting of hydroxyapatite (HAp) microparticles covalently coupled onto a silicone sheet was developed. Initially, an acrylic acid (AAc) -grafted silicone sheet with a 16.7 g/cm 2 surface graft density was prepared by corona-discharge treatment. The surface of sintered, spherical, carbonated HAp particles with an average diameter of 2.0 m was subsequently modified with amino groups. The amino group surface density of the HAp particles was calculated to be approximately one amino molecule per 1.0 nm 2 of particle surface area. These samples were characterized with Fourier transform infrared spectrometry and X-ray photoelectron spectroscopy. After the formation of ammonium ionic bonds between both samples under aqueous conditions, they were reacted at 180°C for 6 h in vacuo to form covalent bonds through a solid-phase condensation. The HAp particles were coupled to the AAcgrafted silicone surface by a covalent linkage. Further improvements in the adhesive and bioactive properties of the HAp-coated silicone material are expected.