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A hydrolase-related transport system is not required to explain the intestinal uptake of glucose liberated from phlorizin

โœ Scribed by Dean A. Warden; Franklin F. Fannin; James O. Evans; Dan W. Hanke; Donald F. Diedrich


Book ID
115724594
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
554 KB
Volume
599
Category
Article
ISSN
0005-2736

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High-affinity phlorizin binding to brush
โœ Tannenbaum, Carl ;Toggenburger, Gerhard ;Kessler, Markus ;Rothstein, Aser ;Semen ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 794 KB

In the presence of an NaSCN gradient phlorizin binds with a high affinity (Kd 4.7 pM) t o vesicles derived from brush border membranes of intestinal cells of rabbits. The value for Kd corresponds closely t o that of Ki determined from phlorizin inhibition of sugar transport. The apparent affinity fo