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A hybrid recognition sequence in a recombinant restriction enzyme and the evolution of DNA sequence specificity

โœ Scribed by Nagaraja, Valakunja; Shepherd, John C. W.; Bickle, Thomas A.


Book ID
109739746
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
291 KB
Volume
316
Category
Article
ISSN
0028-0836

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The distribution of restriction fragment
โœ Th. Jarchau; H. Vogt ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 411 KB

Overlapping subsequences in a DNA sequence are not independent even if independence is supposed for the single nucleotides. Therefore the often used geometric distribution for the length of restriction fragments is not exact. The exact distribution of this random variable is derived for non-overlapp