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A humanized mouse model for a common β0-thalassemia mutation

✍ Scribed by Duangporn Jamsai; Faten Zaibak; Wantana Khongnium; Jim Vadolas; Lucille Voullaire; Kerry J. Fowler; Sophie Gazeas; Suthat Fucharoen; Robert Williamson; Panayiotis A. Ioannou

Book ID
116981371
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
349 KB
Volume
85
Category
Article
ISSN
0888-7543

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A common Chinese β-thalassemia mutation
A common Chinese β-thalassemia mutation found in a Japanese family
✍ Yuji Naritomi; Hitoshi Nakashima; Masaaki Kagimoto; Yasushi Naito; Eisuke Yokota 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 284 KB

We have identified the substitution of a thymine for a cytosine at nucleotide position 654 in the second intron of the [3-globin gene that causes [3-thalassemia in a Japanese family. This mutation was reported to occur rather frequently in patients of Chinese origin, but has rarely been found in oth