A human tumour colony-forming assay
β Scribed by Slee, P. H. Th. J. ;Cleton, F. J. ;van Oosterom, A. I. ;Natarajan, A. T.
- Book ID
- 105524524
- Publisher
- Springer
- Year
- 1986
- Tongue
- Dutch
- Weight
- 190 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1573-739X
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A total of 362 tumor specimens were tested in the Human Tumor Colony-Forming Assay for sensitivity to one of eight drug combinations and to each component drug as a single agent. Peak pharmacologically achievable concentrations of drug were used in continuous exposure. In 175 assays greater than 50%
Over forty papers describing correlations between in vitro human tumor sensitivity to a variety of chemotherapeutic agents and the in vivo response of patients to those agents have been published since the publication in 1978 by Salmon and Hamburger of their results of a human tumor colony-forming c