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A human papillomavirus type 18 E6/E7 transgene sensitizes mouse lens cells to human wild-type p53-mediated apoptosis

โœ Scribed by Nakamura, Takafumi; Williams-Simons, Lisa; Westphal, Heiner


Book ID
110060764
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
946 KB
Volume
14
Category
Article
ISSN
0950-9232

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Human papillomavirus type 16 E6 and HPV-
โœ Yongmin Liu; Ann McKalip; Brian Herman ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 583 KB

We and others have previously reported that human papillomavirus (HPV)-16 E6 protein expression sensitizes certain cell types to apoptosis. To confirm that this sensitization occurred in HPV's natural host cells, and to explore the mechanism(s) of sensitization, we infected human keratinocytes (HKCs