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A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

โœ Scribed by Favera, Riccardo Dalla; Gelmann, Edward P.; Gallo, Robert C.; Wong-Staal, Flossie

Book ID
109723354
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
716 KB
Volume
292
Category
Article
ISSN
0028-0836

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โœ Chang, Esther H.; Furth, Mark E.; Scolnick, Edward M.; Lowy, Douglas R. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 644 KB

A normal human gene homologous to the p21 ras oncogene of Harvey murine sarcoma virus induced oncogenic transformation and high p21 ras levels in murine fibroblasts when this gene was ligated to a control element (the long terminal repeat) from a murine or feline retrovirus. These results indicate t