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A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors

โœ Scribed by Ogden, Kevin K.; Yuan, Hongjie; Hansen, Kasper B.; Zhang, Jing; Gibb, Aladair J.; Traynelis, Stephen F.


Book ID
123413095
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
44 KB
Volume
106
Category
Article
ISSN
0006-3495

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โœ Erdmann, Jeanette; Hegemann, Nina; Weidemann, Alexander; Kallisch, Heike; Hummel ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 21 KB ๐Ÿ‘ 2 views

To elucidate if genetic variants in the bradykinin B2 receptor (B2) gene occur that could affect receptor expression and function, we screened for mutations in the promoter and in the coding region of the human B2 gene. In our initial study we analyzed 92 consecutive, unrelated subjects (including 2