𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A human liposarcoma cell line producing hyaluronic acid

✍ Scribed by R. T. Morgan; L. A. Quinn; G. E. Moore; T. U. Semple; L. K. Woods

Book ID
102668335
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
862 KB
Volume
45
Category
Article
ISSN
0008-543X

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✦ Synopsis

A human liposarcoma cell line COLO 222, derived from a primary tumor in a 62-year-old male, elaborates hyaluronic acid. COLO 222 is characterized on the basis of histochemical, ultramorphological, and cytogenetic properties, along with isozyme phenotype and cell products. A chromosome mode of 53 predominates and unique Giemsa-banded marker chromosomes are identified. An autochthonous lymphoid cell line, COLO 143v, was established after the addition of exogenous Epstein-Barr virus. Cytogenetic analysis of Colo 143v is consistent with a normal male karyotype. COLO 143v possesses B-cell characteristics. This autochthonous system had been used for immunological studies and cytotoxicity assays.

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