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A homoharringtonine-based regimen for childhood acute myelogenous leukemia

✍ Scribed by Tang, JingYan ;Xue, Huiliang ;Pan, Ci ;Chen, Jing ;Gu, LongJun ;Zhao, HuiJun

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 61 KB
Volume: 41
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.10264

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## Abstract ## Background Homoharringtonine (HHT) is a plant alkaloid that is derived from a Chinese evergreen tree. Its mechanism of action is thought to be by inhibition of protein, DNA, and RNA synthesis by inhibition of chain initiation. The treatment of acute myelogenous leukemia (AML) in chi