A Homogeneity Test in Overviews with Group Sequentially Monitored Clinical Trials
โ Scribed by Zhengqing Li; Yan Li
- Book ID
- 110724691
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 487 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0006-341X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We developed an interactive and menu-driven computer program to help investigators design and analyze phase II cancer clinical trials with a group sequential method, namely the sequential probability ratio test or the triangular test. Based on the values selected for the parameters of the trial, the
Simple formulae have been derived for the accurate computation of sample sizes when the two-sample t-test is used. Required sample sizes may be reduced by taking repeated measures, especially if correlations are about equal. In a trial with two parallel groups, repeated measures may be summarized by