A histopathologic comparison between synchronous and single primary oral squamous cell carcinomas: In reply
β Scribed by Waruna L. Dissanayake; Wanninayake M. Tilakaratne
- Book ID
- 116943153
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 98 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1528-395X
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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing Λ90% of all oral carcinomas and accounting for 3β5% of all malignancies. The __WWOX__ gene (WWβdomain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q
## Abstract ## Background Tobacco use increases the risk for squamous cell carcinoma (SCC) of the upper aerodigestive tract. The reported incidence of synchronous second primary tumors in head and neck cancer is approximately 10%. Therefore, patients with oral cancer have routinely undergone βpane