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A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors

✍ Scribed by Sharona E ordon; William N Nagotta


Book ID
116157182
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
673 KB
Volume
14
Category
Article
ISSN
0896-6273

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The CNGA3 gene encodes the A3 subunit of the cone photoreceptor cyclic nucleotide-gated (CNG) channel, an essential component of the phototransduction cascade. Certain mutations in CNGA3 cause autosomal recessive achromatopsia, a retinal disorder characterized by severely reduced visual acuity, lack