A highly stereoselective synthesis of (E)-1-substituted-1,3-dienes

✍ Scribed by R. Block; J. Abecassis

• Publisher: Elsevier Science
• Year: 1982
• Tongue: French
• Weight: 224 KB
• Volume: 23
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)87591-7

✦ Synopsis

E)-l-substituted-l,&dienes are obtained with high stereoselectivity by the thermal extrusion of SO2 from 2-substituted-2,5-dihydrothiophene-1,1-dioxides generated by a retro Diels-Alder reaction.

An application to the synthesis of (E)-9,11-dodecadien-For a recent review see K. Mori, "The total synthesis of natural products", Vol.