A fluorescent probe for biothiols based
A fluorescent probe for biothiols based on the conjugate addition of thiols to α,β-unsaturated ester
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Jun Du; Zhe Yang; Haiping Qi; Xiao-Feng Yang
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Article
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2010
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John Wiley and Sons
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English
⚖ 698 KB
## ABSTRACT A sensitive fluorogenic probe **1** for biothiols was developed based on the Michael addition reaction. The probe **1** was readily synthesized via the reaction of 2‐(4′‐hydroxyphenyl) benzimidazole (HPBI) with acryloyl chloride and shows weak fluorescence emission. Upon mixing with bio