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A highly stereocontrolled synthesis of (−)-kanshone a

✍ Scribed by Michiharu Kato; Masataka Watanabe; Bahlul Z. Awen


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
74 KB
Volume
32
Category
Article
ISSN
0040-4039

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A convenient and mild thermal procedure has been developed for stereoselective 2+4-cycloadditions of electron-rich 1,2-dioxygenated olefins 7 to electron-deficient 3-sulfonyl-2-pyrone 6 allowing isolation of the structurally and stereochemically rich initial bicyclic adducts 8. These bicyclic adduct