✦ LIBER ✦

A highly sensitive lactate editing technique for surface coil spectroscopic imaging in vivo

✍ Scribed by Dr. Dominique Bourgeois; Piotr Kozlowski

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 520 KB
Volume: 29
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910290320

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A lactate editing sequence based on the use of spin‐locking pulses with surface coils is described. The sequence retains more than 90% of the available lactate magnetization and suppresses at least 95% of the lipid signal in a single scan and ca. 99.5% after a simple two step cycle. The technique allows simultaneous observation of lactate and uncoupled metabolites in the range 2 to 3 ppm. The sequence was combined with two‐dimensional spectroscopic imaging to obtain a lactate map of an ischemic rat brain in vivo.

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