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A Highly Sensitive, Excimer-Controlled Molecular Beacon

✍ Scribed by Robert Häner; Sarah M. Biner; Simon M. Langenegger; Tao Meng; Vladimir L. Malinovskii

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
427 KB
Volume
49
Category
Article
ISSN
0044-8249

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A novel strategy is described for highly sensitive DNA detection and point mutation identification based on the combination of reverse molecular beacon with DNA ligase. A 5'-phosphoryl and 3'-ferrocene terminated DNA sequence is used as detection probe, which may be ligated to capture DNA immobilize