Proteolytic Fluorescent Signal Amplifica
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Joong H. Kim; Bong H. Chung
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Article
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2010
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John Wiley and Sons
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English
⚖ 517 KB
## Abstract A new strategy for highly sensitive and rapid protease assay is developed by mediating proteolytic formation of oligonucleotide duplexes and using the duplexes for signal amplification. In the presence of matrix metalloprotease‐2 (MMP‐2), fragmentation of the intact DNA–peptide on gold