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A Highly Rearranged Pentaprenylxanthonoid from the Resin of Garcinia hanburyi

✍ Scribed by Si-Jia Tao; Shu-Hong Guan; Xing-Nuo Li; De-An Guo


Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
186 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Gamboketanol (1), a highly rearranged pentaprenylated xanthonoid, two new caged pentaprenylated xanthonoids, gambogefic acid A (2) and gambogellic acid A (3), together with two known compounds, were isolated from the acetone extract of the resin of Garcinia hanburyi. Their structures were established on the basis of extensive spectroscopic and mass‐spectrometric analyses. The cytotoxicity of compounds 1–3 against HeLa tumor cell line was evaluated, with all of them being modestly active.


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