## Dedicated to Professor Wei-Yuan Huang on the occasion of his 85th birthday The 1,3-dipolar cycloaddition of azomethine ylides to electron-deficient alkenes is one of the most powerful methods for the construction of highly substituted pyrrolidine rings. [1] Following early research on the prepa
A Highly Enantio- and Diastereoselective Cu-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with Nitroalkenes
β Scribed by Xiao-Xia Yan; Qian Peng; Yan Zhang; Kai Zhang; Wei Hong; Xue-Long Hou; Yun-Dong Wu
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 30 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0044-8249
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on the occasion of his 85th birthday The 1,3-dipolar cycloaddition of azomethine ylides to electron-deficient alkenes is one of the most powerful methods for the construction of highly substituted pyrrolidine rings. [1] Following early research on the preparation of optically active pyrrolidines in
The first catalytic endo-selective 1,3-dipolar cycloaddition of azomethine ylides and vinyl phenyl sulfone has been developed successfully. The highly efficient silver acetate (AgOAc)/TF-Bi-phamPhos catalytic system exhibited high reactivity, excellent diastereoselectivity (> 98:2), good enantiosele