A highly efficient strategy for the synthesis of 3-substituted salicylic acids by either directed ortho -lithiation or halogen–metal exchange of substituted MOM protected phenols followed by carboxylation.

✍ Scribed by Lau, Stephen YW; Keay, Brian A

• Book ID: 118151009
• Publisher: NRC Research Press
• Year: 2001
• Tongue: French
• Weight: 175 KB
• Volume: 79
• Category: Article
• ISSN: 0008-4042
• DOI: 10.1139/v01-136