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A Highly Diastereoselective MgI2-Mediated Ring Expansion of Methylenecyclopropanes.

✍ Scribed by Mark E. Scott; Wooseok Han; Mark Lautens


Publisher
John Wiley and Sons
Year
2005
Weight
144 KB
Volume
36
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Diastereoselective
✍ R. J. BOFFEY; M. SANTAGOSTINO; W. G. WHITTINGHAM; J. D. KILBURN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 42 KB

Diastereoselective SmI 2 -Mediated Cascade Radical Cyclizations of Methylenecyclopropane Derivatives -A Synthesis of Paeonilactone B. -Using the title cascade reaction from (VII) to (IX) as key step the natural product paeonilactone B (XIV) is synthesized in an efficient manner. The relative stereoc