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A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

✍ Scribed by Nimet Maherali; Tim Ahfeldt; Alessandra Rigamonti; Jochen Utikal; Chad Cowan; Konrad Hochedlinger

Book ID
116891091
Publisher
Elsevier
Year
2008
Tongue
English
Weight
806 KB
Volume
3
Category
Article
ISSN
1934-5909

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With the advent of induced pluripotent stem cell (iPSC) technology, it is now feasible to generate iPSCs with a defined genotype or disease state. When coupled with direct differentiation to a defined lineage, such as hepatic endoderm (HE), iPSCs would revolutionize the way we study human liver biol