✦ LIBER ✦

A heuristic method to reconstruct the history of sequences subject to recombination

✍ Scribed by Jotun Hein

Book ID: 104653671
Publisher: Springer
Year: 1993
Tongue: English
Weight: 845 KB
Volume: 36
Category: Article
ISSN: 0022-2844
DOI: 10.1007/bf00182187

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✦ Synopsis

Sequences subject to recombination and gene conversion defy phylogenetic analysis by traditional methods since their evolutionary history cannot be adequately summarized by a tree. This study investigates ways to describe their evolutionary history and proposes a method giving a partial reconstruction of this history. Multigene families, viruses, and alleles from within populations experience recombinations/gene conversions, so the questions studied here are relevant for a large body of data and the suggested solutions should be very practical. The method employed was implemented in a program, RecPars, written in C and was used to analyze nine retroviruses.

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