A test of Hardy-Weinberg equilibrium in
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Qiuying Sha; Shuanglin Zhang
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Article
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2011
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John Wiley and Sons
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English
⚖ 180 KB
Testing for Hardy-Weinberg equilibrium (HWE) is used routinely as an important initial step for genotype data quality checking. Departure from HWE can be caused by many factors, such as genotyping errors, population stratification, and disease association, if we use affected individuals only. In a s