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A heteropolymer model study for the mechanism of protein folding

✍ Scribed by Masataka Fukugita; David Lancaster; Mark G. Mitchard


Publisher
Wiley (John Wiley & Sons)
Year
1997
Tongue
English
Weight
913 KB
Volume
41
Category
Article
ISSN
0006-3525

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✦ Synopsis


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('r tnodel (d rundoml~.scll~in(eruc[itrgchuirrs /n [MOdimcn.sitms is .studicd Lt'i[h numericul ,sitnulu(ions {n order [C]
ehicida(e th(~.ji]ldingmechanism oj protein. H),find (hat the model occasionally . SIMN{ .S,li~lding propen.si[~,depending on [he .wqacnce ()/" random namber.y given t~~ [he chuin. H"c.SIIId?I the thertnodynami( and,kirwmu[ic rok'.sin the Waling mechani~m fty grouping the local cnerg~minima jimnd in rhe .simli [ation.s iruo lh~.~tcrvaccording [c) [fw .simijari[~~of Iheir c'wtjiwrnu[i(wts. 1[ i.s .vaggm[ed [ha[ thc k)' .smull d[~limnulitm.s. B 2 .sliggtv[ !ha[ a hierarchical (Ia.vier struci we pla~+.v an irnportunt role in .sclc~[in,qa unique jiidcd .s[ate (nl[ (?i'lhehtlge n umtrcr ffhxal min inra of ht~[~>ropc)l~'tni~rs. @ 1997


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