A heterogeneous strong basic Mg/La mixed oxide catalyst for efficient synthesis of polyfunctionalized pyrans

✍ Scribed by N. Seshu Babu; Nayeem Pasha; K.T. Venkateswara Rao; P.S. Sai Prasad; N. Lingaiah

• Book ID: 104095159
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 110 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.02.154

✦ Synopsis

An efficient synthesis of polyfunctionalized 4H-pyrans is carried out in one pot through condensation of an aldehyde, malononitrile, and an active methylenic diketo compound using a heterogeneous strong basic Mg/La mixed oxide catalyst. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.