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A Heteroallelic Mutant Mouse Model: A New Orthologue for Human Hyperphenylalaninemia

✍ Scribed by Christineh N. Sarkissian; Danielle M. Boulais; J.David McDonald; Charles R. Scriver

Book ID
115639656
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
198 KB
Volume
69
Category
Article
ISSN
1096-7192

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## Abstract Oxidative stress has been implicated in the pathogenesis of numerous human diseases and disorders, but the mechanistic basis often remains enigmatic. The __Sod2__ mutant mouse, which is sensitized to mitochondrial stress, is an ideal mutant model for studying the role of oxidative stres