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A heritable fragile 12q24.13 segregating in a family with the fragile X chromosome

✍ Scribed by Anthony P. Amarose; Peter R. Huttenlocher; Rita M. Sprudzs; Thomas J. Laitsch; Mark J. Pettenati

Publisher: Springer
Year: 1987
Tongue: English
Weight: 395 KB
Volume: 75
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00273829

No coin nor oath required. For personal study only.

✦ Synopsis

A fragile site on chromosome 12, at 12q24.13, was found in the lymphocytes of two members of a family during the study for detection of a fragile X chromosome. The site was found to be heritable and folate-sensitive, and it fulfills all four criteria for a fragile site. It thus can now be confirmed as the heritable fragile site FRA12C.

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