A Graphene Platform for Sensing Biomolecules

✍ Scribed by Chun-Hua Lu; Huang-Hao Yang; Chun-Ling Zhu; Xi Chen; Guo-Nan Chen

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 430 KB
• Volume: 48
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200901479

✦ Synopsis

Abstract

Sensitive platform: The use of graphene oxide (GO) as a platform for the sensitive and selective detection of DNA and proteins is presented. The interaction of GO and dye‐labeled single‐stranded DNA leads to quenching of the dye fluorescence. Conversely, the presence of a target DNA or protein leads to the binding of the dye‐labeled DNA and target, releasing the DNA from GO, thereby restoring the dye fluorescence (see picture).magnified image