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A glycosylation reaction: Conversion of methyl glicosides to glycosyl chlorides by boron trichloride

✍ Scribed by Guillermo R. Perdomo; Jiri J. Krepinsky

Book ID
104228083
Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
256 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis

Methyl glycosides react readily with boron trichloride in dichloromethane solutions at -78 "C to give the corresponding glycosyl chlorides for subsequent use in glycosylation reactions.

This reaction is compatible with the presence of glycosyl linkages in the molecule, as well as benzyl and acetyl protecting groups.

πŸ“œ SIMILAR VOLUMES

A glycosylation reaction: Conversion of
A glycosylation reaction: Conversion of methyl glycosides to glycosyl chlorides by boron trichloride.
✍ G.R. Perdomo; J.J. Krepinsky πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 25 KB

In the last paragraph on page 5596, the fifth line should read as follows: II . ..2.3.4-tri-o-beneyl mannopyranoside 16, 15X;..." In the schematic representation on page 5597, the substituents for compound 7 should be listed as follows: "Rl=NCS; R2=R5=Bn; R4=H."