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A germline TaqI restriction fragment length polymorphism in the progesterone receptor gene in ovarian carcinoma

โœ Scribed by McKenna, NJ; Kieback, DG; Carney, DN; Fanning, M; McLinden, J; Headon, DR


Book ID
109837214
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
990 KB
Volume
71
Category
Article
ISSN
0007-0920

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Direct gene analysis of the haptoglobin gene region was carried out by Southern blotting using an Hp cDNA as probe. Two types of polymorphism were observed: one due to intragenic duplication, is characterized by a constant fragment length difference of 1700bp observed with several enzymes and by com