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A genotypic resistance assay for the detection of drug resistance in the human immunodeficiency virus type 1 envelope gene

✍ Scribed by Kristel Van Laethem; Yoeri Schrooten; Philippe Lemey; Eric Van Wijngaerden; Stéphane De Wit; Marc Van Ranst; Anne-Mieke Vandamme


Book ID
113766907
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
120 KB
Volume
123
Category
Article
ISSN
0166-0934

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## Abstract An assay for the analysis of point mutations in DNA fragments amplified by the polymerase chain reaction is described. The method was applied to the analysis of mutations leading to single amino acid changes in the reverse transcriptase gene of human immunodeficiency virus type‐1 that a