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A genome wide linkage scan for cleft lip and palate and dental anomalies

โœ Scribed by Alexandre R. Vieira; Toby G. McHenry; Sandra Daack-Hirsch; Jeffrey C. Murray; Mary L. Marazita


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
112 KB
Volume
146A
Category
Article
ISSN
1552-4825

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## Abstract Nonโ€syndromic cleft lip with/without cleft palate (CL/P) is a common, usually nonโ€fatal birth defect of complex etiology. Several segregation analyses have demonstrated that genetic factors are important in the pathogenesis of CL/P, most likely through the interaction of several genes o

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## Abstract Cleft lip with or without cleft palate (CL/P) is a common congenital anomaly, with birth prevalence ranging from 1/500 to 1/1,000. A number of genetic loci have shown positive linkage or association results in European Caucasian populations. The purpose of the current study was to asses