✦ LIBER ✦

A genome-wide functional assay of signal transduction in living mammalian cells

✍ Scribed by Negulescu, Paul A.; Whitney, Mike; Rockenstein, Edward; Cantin, Greg; Knapp, Tom; Zlokarnik, Gregor; Sanders, Pam; Durick, Kyle; Craig, Frank F.

Book ID: 109806985
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 328 KB
Volume: 16
Category: Article
ISSN: 1087-0156
DOI: 10.1038/4302

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of Cre recombinase as a repor

Expression of Cre recombinase as a reporter of signal transduction in mammalian cells

✍ Larry C Mattheakis; Susan E Olivan; Jennifer M Dias; Jeffrey P Northrop 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 153 KB

## Background: Cell-based reporter assays, which rely on a reporter gene under the control of a regulated promoter, are widely used to screen chemical libraries for novel receptor ligands. here, we describe a reporter system that is based on ligand-induced dna recombination to express the reporter

A genome-wide RNA interference screen in

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

✍ Nybakken, Kent; Vokes, Steven A; Lin, Ting-Yi; McMahon, Andrew P; Perrimon, Norb 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 808 KB

Multiple signal transduction pathways le

Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells: I. Involvement of protein kinase C–dependent and –independent pathways

✍ Ding-Ji Wang; Ning-Na Huang; Dr. Fernando A. Gonzalez; Leon A. Heppel 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 940 KB

We recently reported that extracellular ATP was mitogenic for Swiss 3T3, 3T6, and A431 cells (Huang et al.: Proc. Natl. Acad. Sci. USA, 86:7904-7908, 1989). Here we examined the possible involvement of activation of the protein kinase C (PKC) signal transduction pathway in the mechanism of action o

A genome-wide study of the repressive ef

A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells

✍ Williams, C; Edvardsson, K; Lewandowski, S A; Ström, A; Gustafsson, J-Å 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 428 KB

S1.12 Demonstration of the presence of p

S1.12 Demonstration of the presence of peptide:N-glycanase activities in mammalian-derived cultured cells. A possible occurrence ofN-glycosylation/de-N-glycosylation system in a wide variety of living organisms as the universal biologic processes

✍ T. Suzuki; A. Seko; K. Kitajima; S. Inoue; Y. Inoue 📂 Article 📅 1993 🏛 Springer US 🌐 English ⚖ 131 KB

Early loss of mammalian target of rapamy

Early loss of mammalian target of rapamycin complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic nuclear factor 1-α (HNF1A) function in INS-1 insulinoma cells

✍ A. M. Farrelly; H. Wobser; C. Bonner; S. Anguissola; M. Rehm; C. G. Concannon; J 📂 Article 📅 2008 🏛 Springer 🌐 English ⚖ 296 KB