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A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26

✍ Scribed by McAuley, E Z; Blair, I P; Liu, Z; Fullerton, J M; Scimone, A; Van Herten, M; Evans, M R; Kirkby, K C; Donald, J A; Mitchell, P B

Book ID: 110060418
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 164 KB
Volume: 14
Category: Article
ISSN: 1359-4184
DOI: 10.1038/sj.mp.4002146

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We completed a genome-wide scan for susceptibility loci for bipolar affective disorders in families derived from a rather homogeneous population in the Province of Que ´bec. The genetic homogeneity of this population stems from the migration of founding families into this relatively isolated area o