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A Genetic Murine Model of Endolymphatic Hydrops: The Phex Mouse

โœ Scribed by Wick, Cameron C. (author);Semaan, Maroun T. (author);Zheng, Qing Yin (author);Megerian, Cliff A. (author)

Book ID
125386450
Publisher
Springer Science and Business Media B.V.
Year
2014
Tongue
English
Weight
511 KB
Volume
2
Category
Article
ISSN
2167-583X

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## Abstract ## Objectives/Hypothesis: Excitotoxic and related inflammatory injury are implicated in the spiral ganglion degeneration seen with Meniere's disease and endolymphatic hydrops (ELH). Excitotoxicity is initiated with glutamate elevation and associated with downstream increases in reactiv