Dissection of mammalian replicators by a
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Toshihiko Hashizume; Noriaki Shimizu
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Article
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2007
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John Wiley and Sons
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English
β 480 KB
## Abstract A plasmid, bearing a mammalian replication initiation region (IR) and a matrix attachment region (MAR) was previously shown to be efficiently amplified to high copy number in mammalian cells and to generate chromosomal homogeneously staining regions (HSRs). The amplification mechanism w