A general synthesis of α-amino acid orthoesters from nitriles via n-chloroimidates
✍ Scribed by W.H. Graham
- Book ID
- 104239453
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 96 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## SR)-(-)-N-[1-(Triethoxymethyl)ethylidene]-p-toluenesulfinamide (2) was synthesized from the addition reaction of triethoxyacetonitrile with MeLi followed by (+)-(R)-d-menthyl p-toluenesulfinate (1R). Sulfinimine 2 underwent complete stereoselective reduction with 9-BBN and addition reaction wit
In connection with our experiments directed toward the design of specific enzyme inhibitors,l we desired an efficient route to vinyl amino acids of type 1. 3 Although these might be obtained by partial reduction of the corresponding ethynyl amino acids as has been shown for a-vinyl DOPA (R = 3,4-di