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A general synthesis of tetrahydropyrazolo[3,4-d]thiazoles

✍ Scribed by Pelletier, Sophie; Pinson, Benjamin; Smejkal, Tomas; Lamberth, Clemens


Book ID
120170693
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
323 KB
Volume
69
Category
Article
ISSN
0040-4020

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## Abstract The synthesis of 7,8‐dihydro‐5(6__H__)‐quinolinone (**3**) from commercially available 3‐amino‐2‐cyclohexen‐1‐one (**1**) and 3‐(dimethylamino)acrolein (**4**) in 23% yield avoids the preparation of propynal (**2**). Conversion of 5‐(4‐methylphenylsulfonyl)‐6,7,8,9‐tetrahydro‐5__H__‐pyr